CD235a/GYPA Protein (AA 20-91) (His tag)
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- Target See all CD235a/GYPA (GYPA) Proteins
- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-91
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD235a/GYPA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPLSTTEVA MHTSTSSSVT KSYISSQTND THKRDTYAAT PRAHEVSEIS VRTVYPPEEE TGERVQLAHH FSEPEHHHHH H
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product GYPA Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
- Alternative Name
- GYPA (GYPA Products)
- Synonyms
- GYPA Protein, gpa Protein, AI853584 Protein, CD235a Protein, GPA Protein, GPErik Protein, GPSAT Protein, HGpMiV Protein, HGpMiXI Protein, HGpSta(C) Protein, MN Protein, MNS Protein, PAS-2 Protein, glycophorin A (MNS blood group) Protein, glycophorin A Protein, GYPA Protein, Gypa Protein
- Background
- GYPA, also known as glycophorin-A isoform 1, is the major transmembrane sialoglycoprotein of red blood cells. It has been shown to contribute to the expression of the MN and Wright blood group antigens, to act as a receptor for the malaria parasite Plasmodium falciparum and Sendai virus, and along with the anion transporter, band 3, may contribute to the mechanical properties of the red blood cell membrane. It expression is locally increased in carotid atherosclerotic lesions of symptomatic compared to asymptomatic patients. Recombinant human GYPA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 9.1kDa (81aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_002090
- UniProt
- P02724
- Pathways
- Maintenance of Protein Location
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