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CD84 Protein (CD84) (AA 22-225) (His tag)

CD84 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN5854844
  • Target See all CD84 Proteins
    CD84
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-225
    Origin
    • 11
    • 4
    Human
    Source
    • 9
    • 3
    • 3
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CD84 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPKDSEIFT VNGILGESVT FPVNIQEPRQ VKIIAWTSKT SVAYVTPGDS ETAPVVTVTH RNYYERIHAL GPNYNLVISD LRMEDAGDYK ADINTQADPY TTTKRYNLQI YRRLGKPKIT QSLMASVNST CNVTLTCSVE KEEKNVTYNW SPLGEEGNVL QIFQTPEDQE LTYTCTAQNP VSNNSDSISA RQLCADIAMG FRTHHTGHHH HHH
    Purity
    > 95 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product CD84 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    CD84
    Alternative Name
    CD84 (CD84 Products)
    Synonyms
    RGD1564553 Protein, A130013D22Rik Protein, CDw84 Protein, SLAMF5 Protein, LY9B Protein, hCD84 Protein, mCD84 Protein, CD84 molecule Protein, CD84 antigen Protein, Cd84 Protein, CD84 Protein
    Background
    CD84, also known as slam family member 5 isoform 1, is a self-binding receptor from the CD150 family that is broadly expressed in hematopoietic cells. It is highly expressed in mast cells and that it contributes to the regulation of FCER1 signaling in SAP- and EAT-2-independent and Fes- and Src homology region 2 domain-containing phosphatase-1-dependent mechanisms. It belongs to the signaling lymphocyte activating molecule family of immunoreceptors, and has an unknown function in CLL cells. Its expression is significantly elevated from the early stages of the disease, and is regulated by macrophage migration inhibitory factor and its receptor, CD74. Recombinant human CD84, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    23.8kDa (213aa) 28-40kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_001171808
    UniProt
    Q9UIB8
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