ATP1B1 Protein (AA 63-303) (His tag)
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- Target See all ATP1B1 Proteins
- ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 63-303
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This ATP1B1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPEFKPTYQ DRVAPPGLTQ IPQIQKTEIS FRPNDPKSYE AYVLNIVRFL EKYKDSAQRD DMIFEDCGDV PSEPKERGDF NHERGERKVC RFKLEWLGNC SGLNDETYGY KEGKPCIIIK LNRVLGFKPK PPKNESLETY PVMKYNPNVL PVQCTGKRDE DKDKVGNVEY FGLGNSPGFP LQYYPYYGKL LQPKYLQPLL AVQFTNLTMD TEIRIECKAY GENIGYSEKD RFQGRFDVKI EVKSHHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is > 3,000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0 pmole of Adenosine 5-triphosphate to phosphate per minute per minute at pH 7.5 at 25C.
- Top Product
- Discover our top product ATP1B1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ATP1B1 (ATPase, Na+/K+ Transporting, beta 1 Polypeptide (ATP1B1))
- Alternative Name
- ATP1B1 (ATP1B1 Products)
- Synonyms
- ATP1B Protein, Atp4b Protein, Atpb Protein, Atpb-1 Protein, NKbeta1 Protein, ATPBS Protein, atp1b1 Protein, atp1b1a Protein, cb710 Protein, ATPase Na+/K+ transporting subunit beta 1 Protein, ATPase, Na+/K+ transporting, beta 1 polypeptide Protein, ATPase beta chain Protein, ATP synthase CF1 beta subunit Protein, ATPase Na+/K+ transporting subunit beta 1 S homeolog Protein, ATPase, Na+/K+ transporting, beta 1b polypeptide Protein, ATP1B1 Protein, Atp1b1 Protein, atpB Protein, atp1b1.S Protein, atp1b1b Protein
- Background
- ATP1B1, also known as ATPase Na+/K+ transporting subunit beta 1, belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Recombinant human ATP1B1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.0kDa (250aa) 28-40KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001668
- UniProt
- P05026
- Pathways
- Thyroid Hormone Synthesis, Ribonucleoside Biosynthetic Process, SARS-CoV-2 Protein Interactome
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