DDR2 Protein (AA 22-399) (His tag)
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- Target See all DDR2 Proteins
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-399
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This DDR2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- KAQVNPAICR YPLGMSGGQI PDEDITASSQ WSESTAAKYG RLDSEEGDGA WCPEIPVEPD DLKEFLQIDL HTLHFITLVG TQGRHAGGHG IEFAPMYKIN YSRDGTRWIS WRNRHGKQVL DGNSNPYDIF LKDLEPPIVA RFVRFIPVTD HSMNVCMRVE LYGCVWLDGL VSYNAPAGQQ FVLPGGSIIY LNDSVYDGAV GYSMTEGLGQ LTDGVSGLDD FTQTHEYHVW PGYDYVGWRN ESATNGYIEI MFEFDRIRNF TTMKVHCNNM FAKGVKIFKE VQCYFRSEAS EWEPNAISFP LVLDDVNPSA RFVTVPLHHR MASAIKCQYH FADTWMMFSE ITFQSDAAMY NNSEALPTSP MAPTTYDPML KVDDSNTRLE HHHHHH
- Purity
- > 90 % by SDS - PAGE.
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product DDR2 Protein
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Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 22-399) protein (His tag)
DDR2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 22-399) protein (His tag)DDR2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) protein (His tag)DDR2 Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 277-377) protein (GST tag)DDR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 1-855) protein (GST tag)DDR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Active) protein (GST tag,His tag)DDR2 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Active) protein (His tag)DDR2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (Active) protein (Fc Tag)DDR2 Origin: Rat Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- Alternative Name
- DDR2 (DDR2 Products)
- Synonyms
- MIG20a Protein, NTRKR3 Protein, TKT Protein, TYRO10 Protein, AW495251 Protein, Ntrkr3 Protein, tyro10 Protein, DDR2 Protein, Tyro10 Protein, ddr2 Protein, si:ch211-193c2.1 Protein, discoidin domain receptor tyrosine kinase 2 Protein, discoidin domain receptor family, member 2 Protein, discoidin domain receptor family, member 2, like Protein, DDR2 Protein, Ddr2 Protein, ddr2l Protein
- Background
- DDR2, also known as discoidin domain-containing receptor 2, belongs to the discoidin-like domain containing subfamily of receptor tyrosine kinases. It is mainly expressed in mesenchymal cells and is unique amog RTKs in that its ligand is fibrillar collagen rather than a growth factor-like peptide. Recombinant human DDR2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 43.7kDa (386aa) 40-57KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001014796
- UniProt
- Q16832
- Pathways
- RTK Signaling
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