14-3-3 eta Protein (YWHAH) (AA 1-246)

Catalog No. ABIN5854575

Product Details

Target: 14-3-3 eta (YWHAH)

Protein Type: Recombinant

Protein Characteristics: AA 1-246

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: 14-3-3 eta (YWHAH)

Alternative Name: 14-3-3 eta (YWHAH Products)

Synonyms: ywha1 Protein, 14-3-3e Protein, YWHAH Protein, YWHA1 Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta Protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta L homeolog Protein, YWHAH Protein, ywhah Protein, Ywhah Protein, ywhah.L Protein

Background: 14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 28.2kDa (246aa)

NCBI Accession: NP_003396

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction