PODXL Protein (AA 22-404) (His tag)
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- Target See all PODXL Proteins
- PODXL (Podocalyxin-Like (PODXL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-404
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This PODXL protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- HNGNETSTSA IKSSTVQSHQ SATTSTEVTT GHPVASTLAS TQPSNPTPFT TSTQSPSMPT STPNPTSNQS GGNLTSSVSE VDKTKTSSPS STAFTSSSGQ TASSGGKSGD SFTTAPTTTL GLINVSSQPT DLNTTSKLLS TPTTDNTTSP QQPVDSSPST ASHPVGQHTP AAVPSSSGST PSTDNSTLTW KPTTHKPLGT SEATQPLTSQ TPGITTLPVS TLQQSMASTV GTTTEEFTHL ISNGTPVAPP GPSTPSPIWA FGNYQLNCEP PIRPDEELLI LNLTRASLCE RSPLDEKEKL VELLCHSVKA SFKPAEDLCT LHVAPILDNQ AVAVKRIIIE TKLSPKAVYE LLKDRWDDLT EAGVSDMKLG KEGPPEVNED RFSLEHHHHH H
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product PODXL Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PODXL (Podocalyxin-Like (PODXL))
- Alternative Name
- Podxl (PODXL Products)
- Synonyms
- Gp200 Protein, PC Protein, PCLP Protein, PCLP-1 Protein, PCB Protein, AW121214 Protein, Ly102 Protein, Pclp1 Protein, podocalyxin Protein, MEP21 Protein, PODXL Protein, Gp135 Protein, PCLP1 Protein, cPCLP1 Protein, podxl Protein, fc18d02 Protein, wu:fc18d02 Protein, Pc Protein, Pcb Protein, Podxl Protein, podocalyxin like Protein, pyruvate carboxylase Protein, podocalyxin-like Protein, PODXL Protein, PC Protein, Podxl Protein, podxl Protein, Pcx Protein
- Background
- PODXL, also known as Podocalyxin, is a heavily glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. This protein involved in the regulation of both adhesion and cell morphology and cancer progression. It has to function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Also, it acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Recombinant mouse PODXL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 41.0kDa (391aa) 70-100KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_038751
- UniProt
- Q9R0M4
- Pathways
- Tube Formation
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