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LIFR Protein (AA 45-833) (His tag)

LIFR Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN5854526
  • Target See all LIFR Proteins
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 45-833
    Origin
    • 10
    • 5
    • 5
    Human
    Source
    • 9
    • 6
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This LIFR protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    ADPQKKGAPH DLKCVTNNLQ VWNCSWKAPS GTGRGTDYEV CIENRSRSCY QLEKTSIKIP ALSHGDYEIT INSLHDFGSS TSKFTLNEQN VSLIPDTPEI LNLSADFSTS TLYLKWNDRG SVFPHRSNVI WEIKVLRKES MELVKLVTHN TTLNGKDTLH HWSWASDMPL ECAIHFVEIR CYIDNLHFSG LEEWSDWSPV KNISWIPDSQ TKVFPQDKVI LVGSDITFCC VSQEKVLSAL IGHTNCPLIH LDGENVAIKI RNISVSASSG TNVVFTTEDN IFGTVIFAGY PPDTPQQLNC ETHDLKEIIC SWNPGRVTAL VGPRATSYTL VESFSGKYVR LKRAEAPTNE SYQLLFQMLP NQEIYNFTLN AHNPLGRSQS TILVNITEKV YPHTPTSFKV KDINSTAVKL SWHLPGNFAK INFLCEIEIK KSNSVQEQRN VTIKGVENSS YLVALDKLNP YTLYTFRIRC STETFWKWSK WSNKKQHLTT EASPSKGPDT WREWSSDGKN LIIYWKPLPI NEANGKILSY NVSCSSDEET QSLSEIPDPQ HKAEIRLDKN DYIISVVAKN SVGSSPPSKI ASMEIPNDDL KIEQVVGMGK GILLTWHYDP NMTCDYVIKW CNSSRSEPCL MDWRKVPSNS TETVIESDEF RPGIRYNFFL YGCRNQGYQL LRSMIGYIEE LAPIVAPNFT VEDTSADSIL VKWEDIPVEE LRGFLRGYLF YFGKGERDTS KMRVLESGRS DIKVKNITDI SQKTLRIADL QGKTSYHLVL RAYTDGGVGP EKSMYVVTKE NSHHHHHH
    Purity
    > 90 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product LIFR Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))
    Alternative Name
    LIFR (LIFR Products)
    Synonyms
    A230075M04Rik Protein, AW061234 Protein, LIF Protein, CD118 Protein, LIF-R Protein, SJS2 Protein, STWS Protein, SWS Protein, leukemia inhibitory factor receptor Protein, LIF receptor alpha Protein, leukemia inhibitory factor receptor alpha Protein, Lifr Protein, LOC397451 Protein, LIFR Protein
    Background
    LIFR, also known as leukemia inhibitory factor receptor, is the receptor for leukemia inhibitory factor, a pleiotropic cytokine affecting the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIFR plays an important role in several aspects of early pregnancy such as blastocyst implantation in the uterus. Recombinant human LIFR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    90.5kDa (798aa) 100-150KDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_002301
    UniProt
    P42702
    Pathways
    JAK-STAT Signaling, Growth Factor Binding
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