VEGFC Protein (AA 112-227) (His tag)

Catalog No. ABIN5854525

Product Details

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Protein Type: Recombinant

Protein Characteristics: AA 112-227

Origin: Human

Source: Baculovirus infected Insect Cells

Purification tag / Conjugate: This VEGFC protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: ADPAHYNTEI LKSIDNEWRK TQCMPREVCI DVGKEFGVAT NTFFKPPCVS VYRCGGCCNS EGLQCMNTST SYLSKTLFEI TVPLSQGPKP VTISFANHTS CRCMSKLDVY RQVHSIIRRH HHHHH

Purity: > 90 % by SDS - PAGE

Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 20 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: VEGFC (VEGFC Products)

Synonyms: VEGFC Protein, vegf-c Protein, xvegf-c Protein, Flt4-L Protein, VRP Protein, AW228853 Protein, VEGF-C Protein, vascular endothelial growth factor c Protein, vascular endothelial growth factor C Protein, vascular endothelial growth factor C S homeolog Protein, vegfc Protein, VEGFC Protein, vegfc.S Protein, Vegfc Protein

Background: VEGFC, also known as vascular endothelial growth factor C, is a member of the VEGF family. This growth factors play key roles in the physiology and pathology of many aspects of the cardiovascular system including hematopoiesis, angiogenesis and vascular permeability. Traces of VEGFC are also detected in brain, liver, thymus, skeletal muscles, spleen, prostate, testis and colon. Unlike other VEGF family members, VEGFC expression is not regulated by hypoxia. Recombinant human VEGFC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 14.2kDa (125aa) 18-28KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_005420

UniProt: P49767

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2