TEK Protein (AA 23-746) (His tag)
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- Target See all TEK Proteins
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-746
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This TEK protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AMDLILINSL PLVSDAETSL TCIASGWHPH EPITIGRDFE ALMNQHQDPL EVTQDVTREW AKKVVWKREK ASKINGAYFC EGRVRGQAIR IRTMKMRQQA SFLPATLTMT VDRGDNVNIS FKKVLIKEED AVIYKNGSFI HSVPRHEVPD ILEVHLPHAQ PQDAGVYSAR YIGGNLFTSA FTRLIVRRCE AQKWGPDCSR PCTTCKNNGV CHEDTGECIC PPGFMGRTCE KACEPHTFGR TCKERCSGPE GCKSYVFCLP DPYGCSCATG WRGLQCNEAC PSGYYGPDCK LRCHCTNEEI CDRFQGCLCS QGWQGLQCEK EGRPRMTPQI EDLPDHIEVN SGKFNPICKA SGWPLPTSEE MTLVKPDGTV LQPNDFNYTD RFSVAIFTVN RVLPPDSGVW VCSVNTVAGM VEKPFNISVK VLPEPLHAPN VIDTGHNFAI INISSEPYFG DGPIKSKKLF YKPVNQAWKY IEVTNEIFTL NYLEPRTDYE LCVQLARPGE GGEGHPGPVR RFTTASIGLP PPRGLSLLPK SQTALNLTWQ PIFTNSEDEF YVEVERRSLQ TTSDQQNIKV PGNLTSVLLS NLVPREQYTV RARVNTKAQG EWSEELRAWT LSDILPPQPE NIKISNITDS TAMVSWTIVD GYSISSIIIR YKVQGKNEDQ HIDVKIKNAT VTQYQLKGLE PETTYHVDIF AENNIGSSNP AFSHELRTLP HSPASADLGG GKMLHHHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product TEK Protein
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TEK Tyrosine Kinase, Endothelial (TEK) (AA 23-748) (Active) protein (Fc Tag)
TEK Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) protein (GST tag)TEK Origin: Human Host: Wheat germ Recombinant WB, AP, AA, ELISA
TEK Tyrosine Kinase, Endothelial (TEK) (AA 770-1122) (Active) protein (GST tag,His tag)TEK Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 91 % as determined by SDS-PAGE Active
TEK Tyrosine Kinase, Endothelial (TEK) (Active) protein (His tag)TEK Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
TEK Tyrosine Kinase, Endothelial (TEK) (Active) protein (Fc Tag)TEK Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
- Alternative Name
- Angiopoietin-1 receptor (TEK Products)
- Synonyms
- TEK Protein, DKFZp469E064 Protein, AA517024 Protein, Cd202b Protein, Hyk Protein, Tie2 Protein, tie-2 Protein, CD202B Protein, TIE-2 Protein, TIE2 Protein, VMCM Protein, VMCM1 Protein, Tie-2 Protein, tie2 Protein, TEK receptor tyrosine kinase Protein, angiopoietin-1 receptor Protein, TEK tyrosine kinase, endothelial Protein, TEK Protein, LOC100408334 Protein, tek Protein, Tek Protein
- Background
- TEK, also known as angiopoietin-1 receptor isoform 2, is cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4. It regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton. This protein effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Recombinant mouse TEK, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 81.6kDa (730aa) 70-100KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001277478
- UniProt
- Q02858
- Pathways
- RTK Signaling, Growth Factor Binding
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