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TARBP2 Protein (AA 1-345)

TARBP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN5853732
  • Target See all TARBP2 Proteins
    TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-345
    Origin
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Sequence
    MLAANPGKTP ISLLQEYGTR IGKTPVYDLL KAEGQAHQPN FTFRVTVGDT SCTGQGPSKK AAKHKAAEVA LKHLKGGSML EPALEDSSSF SPLDSSLPED IPVFTAAAAA TPVPSVVLTR SPPMELQPPV SPQQSECNPV GALQELVVQK GWRLPEYTVT QESGPAHRKE FTMTCRVERF IEIGSGTSKK LAKRNAAAKM LLRVHTVPLD ARDGNEVEPD DDHFSIGVGS RLDGLRNRGP GCTWDSLRNS VGEKILSLRS CSLGSLGALG PACCRVLSEL SEEQAFHVSY LDIEELSLSG LCQCLVELST QPATVCHGSA TTREAARGEA ARRALQYLKI MAGSK
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product TARBP2 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.4M urea
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))
    Alternative Name
    TARBP2 (TARBP2 Products)
    Synonyms
    trbp Protein, trbp1 Protein, trbp2 Protein, MGC97783 Protein, TARBP2 Protein, LOQS Protein, TRBP Protein, TRBP1 Protein, TRBP2 Protein, fj51e12 Protein, wu:fj51e12 Protein, zgc:63778 Protein, Prbp Protein, TAR (HIV-1) RNA binding protein 2 Protein, TARBP2, RISC loading complex RNA binding subunit Protein, TAR (HIV-1) RNA binding protein 2 L homeolog Protein, TAR (HIV) RNA binding protein 2 Protein, tarbp2 Protein, TARBP2 Protein, tarbp2.L Protein, Tarbp2 Protein
    Background
    TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. This protein contains 3 DRBM (double-stranded RNA-binding) domains. It may also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. TARBP2 binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. Recombinant human TARBP2 protein was expressed in E.coli.
    Molecular Weight
    36.9 kDa (345aa)
    NCBI Accession
    NP_004169
    UniProt
    Q15633
    Pathways
    Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization
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