Calpain S1 Protein (AA 84-268) (His tag)
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- Target See all Calpain S1 (CAPNS1) Proteins
- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 84-268
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Calpain S1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSRTHYSNI EANESEEVRQ FRRLFAQLAG DDMEVSATEL MNILNKVVTR HPDLKTDGFG IDTCRSMVAV MDSDTTGKLG FEEFKYLWNN IKRWQAIYKQ FDTDRSGTIC SSELPGAFEA AGFHLNEHLY NMIIRRYSDE SGNMDFDNFI SCLVRLDAMF RAFKSLDKDG TGQIQVNIQE WLQLTMYS
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CAPNS1 Protein
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Calpain, Small Subunit 1 (CAPNS1) (AA 172-260) protein (GST tag)
CAPNS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Calpain, Small Subunit 1 (CAPNS1) (AA 1-268) protein (GST tag)CAPNS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Calpain, Small Subunit 1 (CAPNS1) (AA 1-268), (full length) protein (His-SUMO Tag)CAPNS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Calpain, Small Subunit 1 (CAPNS1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CAPNS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Calpain, Small Subunit 1 (CAPNS1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CAPNS1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
- Alternative Name
- CAPNS1 (CAPNS1 Products)
- Synonyms
- 30K Protein, CALPAIN4 Protein, CANP Protein, CANPS Protein, CAPN4 Protein, CDPS Protein, CSS1 Protein, Capn4 Protein, CAPNS1 Protein, Capa-4 Protein, Capa4 Protein, D7Ertd146e Protein, MGC84330 Protein, capns1 Protein, cb616 Protein, wu:fb81g08 Protein, wu:fl09e04 Protein, zgc:110603 Protein, calpain small subunit 1 Protein, calpain, small subunit 1 Protein, calpain, small subunit 1 L homeolog Protein, calpain, small subunit 1 a Protein, CAPNS1 Protein, Capns1 Protein, capns1.L Protein, capns1a Protein
- Background
- Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Recombinant human CAPNS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 23.8kDa (208aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001740
- UniProt
- P04632
- Pathways
- Apoptosis
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