Prothrombin Protein (AA 328-622)
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- Target See all Prothrombin (F2) Proteins
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 328-622
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MTFGSGEADC GLRPLFEKKS LEDKTERELL ESYIDGRIVE GSDAEIGMSP WQVMLFRKSP QELLCGASLI SDRWVLTAAH CLLYPPWDKN FTENDLLVRI GKHSRTRYER NIEKISMLEK IYIHPRYNWR ENLDRDIALM KLKKPVAFSD YIHPVCLPDR ETAASLLQAG YKGRVTGWGN LKETWTANVG KGQPSVLQVV NLPIVERPVC KDSTRIRITD NMFCAGYKPD EGKRGDACEG DSGGPFVMKS PFNNRWYQMG IVSWGEGCDR DGKYGFYTHV FRLKKWIQKV IDQFGE
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product F2 Protein
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Coagulation Factor II (thrombin) (F2) (AA 263-362) protein (GST tag)
F2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor II (thrombin) (F2) (AA 1-622) protein (GST tag)F2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor II (thrombin) (F2) (Active) protein (His tag)F2 Origin: Mouse Host: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- Alternative Name
- F2 (F2 Products)
- Synonyms
- PT Protein, RPRGL2 Protein, THPH1 Protein, Cf-2 Protein, Cf2 Protein, FII Protein, thrombin Protein, zgc:66319 Protein, wu:fb57c10 Protein, wu:fd42e09 Protein, wu:fd59d01 Protein, prothrombin Protein, F2 Protein, coagulation factor II, thrombin Protein, coagulation factor II Protein, coagulation factor II (thrombin) Protein, F2 Protein, f2 Protein
- Background
- Coagulation factor II, also known as F2, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Recombinant human F2 protein was expressed in E.coli.
- Molecular Weight
- 33.9kDa (296aa)
- NCBI Accession
- NP_000497
- UniProt
- P00734
- Pathways
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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