MOAP1 Protein (AA 1-351) (His tag)
MOAP1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 85 % by SDS - PAGE
SDS
1 image
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- Target See all MOAP1 Proteins
- MOAP1 (Modulator of Apoptosis 1 (MOAP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-351
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MOAP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMTLRLLE DWCRGMDMNP RKALLIAGIS QSCSVAEIEE ALQAGLAPLG EYRLLGRMFR RDENRKVALV GLTAETSHAL VPKEIPGKGG IWRVIFKPPD PDNTFLSRLN EFLAGEGMTV GELSRALGHE NGSLDPEQGM IPEMWAPMLA QALEALQPAL QCLKYKKLRV FSGRESPEPG EEEFGRWMFH TTQMIKAWQV PDVEKRRRLL ESLRGPALDV IRVLKINNPL ITVDECLQAL EEVFGVTDNP RELQVKYLTT YQKDEEKLSA YVLRLEPLLQ KLVQRGAIER DAVNQARLDQ VIAGAVHKTI RRELNLPEDG PAPGFLQLLV LIKDYEAAEE EEALLQAILE GNFT
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product MOAP1 Protein
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Modulator of Apoptosis 1 (MOAP1) (AA 1-351) protein (GST tag)
MOAP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Modulator of Apoptosis 1 (MOAP1) protein (Myc-DYKDDDDK Tag)MOAP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- MOAP1 (Modulator of Apoptosis 1 (MOAP1))
- Alternative Name
- MOAP1 (MOAP1 Products)
- Synonyms
- MOAP1 Protein, MAP-1 Protein, PNMA4 Protein, AA987038 Protein, Map-1 Protein, Pnma4 Protein, modulator of apoptosis 1 Protein, modulator of apoptosis 1 S homeolog Protein, MOAP1 Protein, moap1.S Protein, Moap1 Protein
- Background
- Modulator of apoptosis 1, also known as MOAP1, belongs to the PNMA family and contains one BH3-like domain and one RASSF1-binding domain. It is required for death receptor-dependent apoptosis. MOAP1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X(L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MOAP1 mediates apoptosis through a mechanism that involves binding to Bax. Recombinant human MOAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 41.9 kDa (374aa)
- NCBI Accession
- NP_071434
- UniProt
- Q96BY2
- Pathways
- Positive Regulation of Endopeptidase Activity
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