DUSP26 Protein (AA 1-211) (His tag)
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- Target See all DUSP26 Proteins
- DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-211
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DUSP26 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMCPGNWL WASMTFMARF SRSSSRSPVR TRGTLEEMPT VQHPFLNVFE LERLLYTGKT ACNHADEVWP GLYLGDQDMA NNRRELRRLG ITHVLNASHS RWRGTPEAYE GLGIRYLGVE AHDSPAFDMS IHFQTAADFI HRALSQPGGK ILVHCAVGVS RSATLVLAYL MLYHHLTLVE AIKKVKDHRG IIPNRGFLRQ LLALDRRLRQ GLEA
- Purity
- > 85 % by SDS - PAGE
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Dual Specificity Phosphatase 26 (DUSP26) (AA 1-110) protein (GST tag)
DUSP26 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Dual Specificity Phosphatase 26 (DUSP26) (AA 1-211) protein (GST tag)DUSP26 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Dual Specificity Phosphatase 26 (DUSP26) (AA 1-211), (full length) protein (His-SUMO Tag)DUSP26 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
- Alternative Name
- DuSP26 (DUSP26 Products)
- Synonyms
- DUSP24 Protein, LDP-4 Protein, MKP8 Protein, NATA1 Protein, SKRP3 Protein, 2310043K02Rik Protein, Skrp3 Protein, RGD1310090 Protein, dual specificity phosphatase 26 Protein, dual specificity phosphatase 26 (putative) Protein, DUSP26 Protein, Dusp26 Protein
- Background
- DuSP26 inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. This protein inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. DuSP26 can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Recombinant human DuSP26 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Molecular Weight
- 26.3 kDa (234aa)
- NCBI Accession
- NP_076930
- UniProt
- Q9BV47
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