NDUFV2 Protein (AA 33-249) (His tag)

Catalog No. ABIN5853221

Product Details

Target: NDUFV2 (NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2))

Protein Type: Recombinant

Protein Characteristics: AA 33-249

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NDUFV2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSGAGGALF VHRDTPENNP DTPFDFTPEN YKRIEAIVKN YPEGHKAAAV LPVLDLAQRQ NGWLPISAMN KVAEVLQVPP MRVYEVATFY TMYNRKPVGK YHIQVCTTTP CMLRNSDSIL EAIQKKLGIK VGETTPDKLF TLIEVECLGA CVNAPMVQIN DNYYEDLTAK DIEEIIDELK AGKIPKPGPR SGRFSCEPAG GLTSLTEPPK GPGFGVQAGL

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: NDUFV2 (NADH Dehydrogenase (Ubiquinone) Flavoprotein 2, 24kDa (NDUFV2))

Alternative Name: NDuFV2 (NDUFV2 Products)

Synonyms: CI-24k Protein, 2900010C23Rik Protein, GB17038 Protein, NuoE Protein, DDBDRAFT_0189294 Protein, DDBDRAFT_0233206 Protein, DDB_0189294 Protein, DDB_0233206 Protein, zgc:73198 Protein, NADH:ubiquinone oxidoreductase core subunit V2 Protein, NADH dehydrogenase (ubiquinone) flavoprotein 2 Protein, NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial Protein, NADH dehydrogenase Protein, NADH dehydrogenase [ubiquinone] flavoprotein 2,mitochondrial Protein, NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa Protein, NDUFV2 Protein, Ndufv2 Protein, LOC409793 Protein, ndufv2 Protein, LOC657790 Protein

Background: The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. NDuFV2 is the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. Recombinant human NDuFV2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 26.1 kDa (240aa) confirmed by MALDI-TOF

NCBI Accession: NP_066552

UniProt: P19404