PSG5 Protein (AA 35-335) (His tag)
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- Target See all PSG5 Proteins
- PSG5 (Pregnancy Specific beta-1-Glycoprotein 5 (PSG5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 35-335
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PSG5 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSQVTIEAL PPKVSEGKDV LLLVHNLPQN LAGYIWYKGQ LMDLYHYITS YVVDGQINIY GPAYTGRETV YSNASLLIQN VTREDAGSYT LHIIKRGDRT RGVTGYFTFN LYLKLPKPYI TINNSKPREN KDVLAFTCEP KSENYTYIWW LNGQSLPVSP RVKRPIENRI LILPSVTRNE TGPYECEIRD RDGGMRSDPV TLNVLYGPDL PSIYPSFTYY RSGENLYLSC FAESNPPAEY FWTINGKFQQ SGQKLSIPQI TTKHRGLYTC SVRNSATGKE SSKSMTVEVS APSGIGRLPL LNPI
- Purity
- > 80 % by SDS - PAGE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 1M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- PSG5 (Pregnancy Specific beta-1-Glycoprotein 5 (PSG5))
- Alternative Name
- PSG5 (PSG5 Products)
- Background
- PSG5 is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSG5 function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Recombinant human PSG5 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 36.4 kDa (324aa)
- NCBI Accession
- NP_001123486
- UniProt
- Q15238
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