TCEA2 Protein (AA 1-299) (His tag)

Catalog No. ABIN5853007

Product Details

Target: TCEA2 (Transcription Elongation Factor A2 (TCEA2))

Protein Type: Recombinant

Protein Characteristics: AA 1-299

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This TCEA2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMMGKEEE IARIARRLDK MVTKKSAEGA MDLLRELKAM PITLHLLQST RVGMSVNALR KQSSDEEVIA LAKSLIKSWK KLLDASDAKA RERGRGMPLP TSSRDASEAP DPSRKRPELP RAPSTPRITT FPPVPVTCDA VRNKCREMLT AALQTDHDHV AIGADCERLS AQIEECIFRD VGNTDMKYKN RVRSRISNLK DAKNPDLRRN VLCGAITPQQ IAVMTSEEMA SDELKEIRKA MTKEAIREHQ MARTGGTQTD LFTCGKCRKK NCTYTQVQTR SSDEPMTTFV VCNECGNRWK FC

Purity: > 85 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 1  mM DTT, 30 % glycerol, 0.25M NaCl

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: TCEA2 (Transcription Elongation Factor A2 (TCEA2))

Alternative Name: TCEA2 (TCEA2 Products)

Synonyms: zgc:56325 Protein, TFIIS Protein, AI326274 Protein, S-II-T1 Protein, SII-T1 Protein, Tceat Protein, transcription elongation factor A (SII), 2 Protein, transcription elongation factor A2 Protein, tcea2 Protein, TCEA2 Protein, Tcea2 Protein

Background: TCEA2 is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human TCEA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 36kDa (322aa), confirmed by MALDI-TOF

NCBI Accession: NP_003186

UniProt: Q15560