GAL Protein (AA 20-123) (His tag)
-
- Target See all GAL Proteins
- GAL (Galanin Prepropeptide (GAL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-123
- Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GAL protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSASAGLWS PAKEKRGWTL NSAGYLLGPH AVGNHRSFSD KNGLTSKREL RPEDDMKPGS FDRSIPENNI MRTIIEFLSF LHLKEAGALD RLLDLPAAAS SEDIERS
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product GAL Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- GAL (Galanin Prepropeptide (GAL))
- Alternative Name
- GAL (GAL Products)
- Synonyms
- xgal Protein, galanin Protein, Galn Protein, GALN Protein, GAL-GMAP Protein, GLNN Protein, GMAP Protein, galanin prepropeptide, gene 2 Protein, galanin Protein, galanin and GMAP prepropeptide Protein, gal.2 Protein, Gal Protein, GAL Protein
- Background
- Galanin peptides preproprotein, also known as GAL, is localized in brain pathways involved in both cognition and affect, and may inhibit learning and memory by inhibiting neurotransmitter release and neuronal firing rate. It modulates a variety of physiological processed including cognition/memory, sensory/pain processing, neurotransmitter/hormone secretion, and feeding behavior. GAL is upregulated in primary afferent and sympathetic neurones and may be involved in the development of sympathetic perineuronal baskets (rings) following nerve injury. Recombinant human GAL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 13.9kDa (127aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_057057
- UniProt
- P22466
- Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Feeding Behaviour
-