CD8B Protein (AA 564-1049) (His tag)
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- Target See all CD8B Proteins
- CD8B (CD8b Molecule (CD8B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 564-1049
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This CD8B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPLQQTPAY IKVQTNKMVM LSCEAKISLS NMRIYWLRQR QAPSSDSHHE FLALWDSAKG TIHGEEVEQE KIAVFRDASR FILNLTSVKP EDSGIYFCMI VGSPELTFGK GTQLSVVDFL PTTAQPTKKS TLKKRVCRLP RPETQKGPLC SPHHHHHH
- Purity
- > 85 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CD8B (CD8b Molecule (CD8B))
- Alternative Name
- CD8B (CD8B Products)
- Synonyms
- Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein
- Background
- CD8B, also known as T-cell surface glycoprotein CD8 beta chain isoform 5, is a cell surface transmembrane glycoprotein. This protein serves as a co-receptor for the T cell receptor (TCR). It found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-alpha and CD8-beta chain. Both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. Recombinant human CD8B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 17.8kDa (158aa) 18-28kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_004922
- UniProt
- P10966
- Pathways
- TCR Signaling
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