IL12RB2 Protein (AA 24-622, Extracellular) (His tag)
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- Target See all IL12RB2 Proteins
- IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 24-622
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This IL12RB2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- KIDACKRGDV TVKPSHVILL GSTVNITCSL KPRQGCFHYS RRNKLILYKF DRRINFHHGH SLNSQVTGLP LGTTLFVCKL ACINSDEIQI CGAEIFVGVA PEQPQNLSCI QKGEQGTVAC TWERGRDTHL YTEYTLQLSG PKNLTWQKQC KDIYCDYLDF GINLTPESPE SNFTAKVTAV NSLGSSSSLP STFTFLDIVR PLPPWDIRIK FQKASVSRCT LYWRDEGLVL LNRLRYRPSN SRLWNMVNVT KAKGRHDLLD LKPFTEYEFQ ISSKLHLYKG SWSDWSESLR AQTPEEEPTG MLDVWYMKRH IDYSRQQISL FWKNLSVSEA RGKILHYQVT LQELTGGKAM TQNITGHTSW TTVIPRTGNW AVAVSAANSK GSSLPTRINI MNLCEAGLLA PRQVSANSEG MDNILVTWQP PRKDPSAVQE YVVEWRELHP GGDTQVPLNW LRSRPYNVSA LISENIKSYI CYEIRVYALS GDQGGCSSIL GNSKHKAPLS GPHINAITEE KGSILISWNS IPVQEQMGCL LHYRIYWKER DSNSQPQLCE IPYRVSQNSH PINSLQPRVT YVLWMTALTA AGESSHGNER EFCLQGKAN
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product IL12RB2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
- Alternative Name
- I12R2 (IL12RB2 Products)
- Synonyms
- IL12RB2 Protein, A930027I18Rik Protein, IL-12RB2 Protein, Ifnm Protein, interleukin 12 receptor subunit beta 2 Protein, interleukin 12 receptor, beta 2 Protein, IL12RB2 Protein, Il12rb2 Protein
- Background
- Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
- Molecular Weight
- 69.7 kDa
- UniProt
- Q99665
- Pathways
- JAK-STAT Signaling
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