TANK Protein (AA 1-119, partial) (His tag)
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- Target See all TANK Proteins
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-119, partial
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This TANK protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product TANK Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- Alternative Name
- TANK (TANK Products)
- Synonyms
- I-TRAF Protein, ITRAF Protein, TRAF2 Protein, C86182 Protein, E430026L09Rik Protein, zgc:153048 Protein, i-traf Protein, tank Protein, traf2 Protein, TRAF family member associated NFKB activator Protein, TRAF family member-associated Nf-kappa B activator Protein, TRAF family member-associated NFKB activator Protein, TRAF family member associated NFKB activator L homeolog Protein, TANK Protein, Tank Protein, tank Protein, tank.L Protein
- Background
- Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining th in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.
- Molecular Weight
- 15.6 kDa
- UniProt
- Q92844
- Pathways
- p53 Signaling, TLR Signaling, Activation of Innate immune Response
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