REG3g Protein (AA 27-174) (His tag)
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- Target See all REG3g Proteins
- REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-174
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Origin
- Mouse
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Source
- Yeast
- Purification tag / Conjugate
- This REG3g protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- EVAKKDAPSS RSSCPKGSRA YGSYCYALFS VSKNWYDADM ACQKRPSGHL VSVLSGAEAS FLSSMIKSSG NSGQYVWIGL HDPTLGYEPN RGGWEWSNAD VMNYINWETN PSSSSGNHCG TLSRASGFLK WRENYCNLEL PYVCKFKA
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product REG3g Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- REG3g (Regenerating Islet Derived Protein 3 gamma (REG3g))
- Alternative Name
- REG3G (REG3g Products)
- Synonyms
- LPPM429 Protein, PAP IB Protein, PAP-1B Protein, PAP1B Protein, PAPIB Protein, REG III Protein, REG-III Protein, UNQ429 Protein, AI449515 Protein, PAPIII Protein, Pap3 Protein, REG3A Protein, regenerating family member 3 gamma Protein, regenerating islet-derived 3 gamma Protein, REG3G Protein, Reg3g Protein
- Background
- Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury
- Molecular Weight
- 18.3 kDa
- UniProt
- O09049
- Pathways
- Activation of Innate immune Response
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