HSD11B2 Protein (AA 1-405, full length) (His tag)
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- Target See all HSD11B2 Proteins
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-405
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This HSD11B2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MERWPWPSGG AWLLVAARAL LQLLRSDLRL GRPLLAALAL LAALDWLCQR LLPPPAALAV LAAAGWIALS RLARPQRLPV ATRAVLITGC DSGFGKETAK KLDSMGFTVL ATVLELNSPG AIELRTCCSP RLRLLQMDLT KPGDISRVLE FTKAHTTSTG LWGLVNNAGH NEVVADAELS PVATFRSCME VNFFGALELT KGLLPLLRSS RGRIVTVGSP AGDMPYPCLG AYGTSKAAVA LLMDTFSCEL LPWGVKVSII QPGCFKTESV RNVGQWEKRK QLLLANLPQE LLQAYGKDYI EHLHGQFLHS LRLAMSDLTP VVDAITDALL AARPRRRYYP GQGLGLMYFI HYYLPEGLRR RFLQAFFISH CLPRALQPGQ PGTTPPQDAA QDPNLSPGPS PAVAR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product HSD11B2 Protein
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Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) protein (GST tag)
HSD11B2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 71-170) protein (GST tag)HSD11B2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) protein (Myc-DYKDDDDK Tag)HSD11B2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
- Alternative Name
- DHI2 (HSD11B2 Products)
- Synonyms
- MGC81883 Protein, 11-HSD2 Protein, AME Protein, AME1 Protein, HSD11K Protein, HSD2 Protein, SDR9C3 Protein, 11HSD2 Protein, HSD11B2 Protein, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog Protein, hydroxysteroid 11-beta dehydrogenase 2 Protein, hsd11b2.L Protein, HSD11B2 Protein, Hsd11b2 Protein
- Background
- Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
- Molecular Weight
- 46.1 kDa
- UniProt
- P80365
- Pathways
- Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
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