CENPA Protein (AA 1-134, full length) (His tag)
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- Target See all CENPA Proteins
- CENPA (Centromere Protein A (CENPA))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-134
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Origin
- Mouse
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Source
- Yeast
- Purification tag / Conjugate
- This CENPA protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGPRRKPQTP RRRPSSPAPG PSRQSSSVGS QTLRRRQKFM WLKEIKTLQK STDLLFRKKP FSMVVREICE KFSRGVDFWW QAQALLALQE AAEAFLIHLF EDAYLLSLHA GRVTLFPKDI QLTRRIRGFE GGLP
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CENPA Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CENPA (Centromere Protein A (CENPA))
- Alternative Name
- CENPA (CENPA Products)
- Synonyms
- CENP-A Protein, CenH3 Protein, Cenp-A Protein, cenpx Protein, cenp-a Protein, sim2 Protein, Cenp-a Protein, RGD1563607 Protein, CENPA Protein, centromere protein A Protein, centromere protein-A Protein, centromeric histone-3 like protein Protein, centromere-specific histone H3 CENP-A Protein, cenp-A Protein, centromere protein A L homeolog Protein, histone H3-like centromeric protein A Protein, CENPA Protein, Cenpa Protein, CENP-A Protein, cenpa Protein, cenp-A Protein, cnp1 Protein, HAN_3g422 Protein, Cenp-a Protein, cenpa.L Protein, CMU_016480 Protein
- Background
- Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assbly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro) .
- Molecular Weight
- 17.51 kDa
- UniProt
- O35216
- Pathways
- Chromatin Binding, Maintenance of Protein Location
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