MAP3K1 Protein (AA 1216-1493, partial) (His tag)
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- Target See all MAP3K1 Proteins
- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
- Protein Type
- Recombinant
- Protein Characteristics
- partial, AA 1216-1493
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MAP3K1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- TALQRRRVAE RPADRPRSIF FLLPSTGCGD WDFNGCETGD VRQKHILRAG GGGGSVEGRD PDDGSPQPSK HHPDAGGHVR EEQLQPLHVD GGRICGSPLE IRSFQGVSRH LHAVTPWPFL SPREPDHSQR RQRCQPAHQH RSEAENCRLW SCCQVGIKRN RCRRVPGTVT GDNCIHGAGP KRSAVWELCM ECWLRHYRNG LCKTTLECRK TLQSSRLDID CRNYCTVHPV TPVPGSARRG AALLRTSASG PASVQRAAET SGLPYHV
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product MAP3K1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
- Alternative Name
- M3K1 (MAP3K1 Products)
- Synonyms
- MAP3K1 Protein, Mekk1 Protein, MAPKKK1 Protein, MEKK1 Protein, Mekk Protein, ARAKIN Protein, ATMEKK1 Protein, MAPK/ERK kinase kinase 1 Protein, MAPKKK8 Protein, T15F16.5 Protein, T15F16_5 Protein, MEKK Protein, MEKK 1 Protein, SRXY6 Protein, mitogen-activated protein kinase kinase kinase 1 Protein, mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase Protein, MAPK/ERK kinase kinase 1 Protein, MAP3K1 Protein, map3k1 Protein, Map3k1 Protein, MEKK1 Protein
- Background
- Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
- Molecular Weight
- 33.7 kDa
- UniProt
- Q13233
- Pathways
- MAPK Signaling, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
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