Cytokeratin 5 Protein (AA 2-198) (GST tag)
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- Target See all Cytokeratin 5 (KRT5) Proteins
- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-198
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Cytokeratin 5 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- HSEAEESKEV ATDVFNSKNL AVQAQKKILG KMVSKSIATT LIDDTSSEVL DELYRVTREY TQNKKEAEKI IKNLIKTVIK LAILYRNNQF NQDELALMEK FKKKVHQLAM TVVSFHQVDY TFDRNVLSRL LNECREMLHQ IIQRHLTAKS HGRVNNVFDH FSDCEFLAAL YNPFGNFKPH LQKLCDGINK MLDEENI
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product KRT5 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
- Alternative Name
- TFIP8 (KRT5 Products)
- Synonyms
- 3300001P10Rik Protein, AW146334 Protein, CK5 Protein, K5 Protein, Krt2-5 Protein, Tfip8 Protein, DDD Protein, DDD1 Protein, EBS2 Protein, KRT5A Protein, Sak57 Protein, ckii Protein, wu:fb02h09 Protein, wu:fj02d02 Protein, wu:fk78b12 Protein, zfCKII Protein, KRT75 Protein, CK-5 Protein, Keratin-5 Protein, keratin 5 Protein, Krt5 Protein, KRT5 Protein, krt5 Protein
- Background
- Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
- Molecular Weight
- 50.3 kDa
- UniProt
- O95379
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