TTF1 Protein (AA 11-242, partial) (His tag)
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- Target See all TTF1 Proteins
- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 11-242, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TTF1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- TPVSDKKKKK CSIHKERPQK HSHEIFRDSS LVNEQSQITR RKKRKKDFQH LISSPLKKSR ICDETANATS TLKKRKKRRY SALEVDEEAG VTVVLVDKEN INNTPKHFRK DVDVVCVDMS IEQKLPRKPK TDKFQVLAKS HAHKSEALHS KVREKKNKKH QRKAASWESQ RARDTLPQSE SHQEESWLSV GPGGEITELP ASAHKNKSKK KKKKSSNREY E
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product TTF1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))
- Alternative Name
- TTF1 (TTF1 Products)
- Synonyms
- TTF-1 Protein, TTF-I Protein, AV245725 Protein, RGD1565673 Protein, transcription termination factor 1 Protein, transcription termination factor, RNA polymerase I Protein, TTF1 Protein, Ttf1 Protein
- Background
- Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
- Molecular Weight
- 29.7 kDa
- UniProt
- Q15361
- Pathways
- Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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