PDCD6 Protein (AA 1-191, full length) (GST tag)
-
- Target See all PDCD6 Proteins
- PDCD6 (Programmed Cell Death 6 (PDCD6))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-191
- Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PDCD6 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PDCD6 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- PDCD6 (Programmed Cell Death 6 (PDCD6))
- Alternative Name
- PDCD6 (PDCD6 Products)
- Synonyms
- pdcd6 Protein, MGC52821 Protein, MGC132114 Protein, zgc:63952 Protein, PDCD6 Protein, ALG-2 Protein, PEF1B Protein, AV299538 Protein, Alg2 Protein, MA-3 Protein, PS2 Protein, alg-2 Protein, programmed cell death 6 L homeolog Protein, programmed cell death 6 Protein, pdcd6.L Protein, pdcd6 Protein, PDCD6 Protein, Pdcd6 Protein
- Background
- Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca2+-regulated signals along the death pathway . Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis, the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Ses to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca2+ affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.5 Publications
- Molecular Weight
- 49.3 kDa
- UniProt
- O75340
- Pathways
- Positive Regulation of Endopeptidase Activity
-