GRK2 Protein (AA 2-634, partial) (His tag)
ADRBK1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
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- Target See all GRK2 (ADRBK1) Proteins
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Protein Type
- Recombinant
- Protein Characteristics
- partial, AA 2-634
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GRK2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADLEAVLADV SYLMAMEKSK ATPAARASKK ILLPEPSIRS VMQKYLEDRG EVTFEKIFSQ KLGYLLFRDF CLNHLEEARP LVEFYEEIKK YEKLETEEER VARSREIFDS YIMKELLACS HPFSKSATEH VQGHLGKKQV PPDLFQPYIE EICQNLRGDV FQKFIESDKF TRFCQWKNVE LNIHLTMNDF SVHRIIGRGG FGEVYGCRKA DTGKMYAMKC
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product ADRBK1 Protein
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Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 1-689) protein (GST tag)
ADRBK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) protein (Myc-DYKDDDDK Tag)ADRBK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Alternative Name
- ARBK1 (ADRBK1 Products)
- Synonyms
- Adrbk-1 Protein, Bark-1 Protein, GRK2 Protein, betaARK1 Protein, BARK1 Protein, BETA-ARK1 Protein, GRK-2 Protein, Grk2 Protein, beta-adrenergic receptor kinase 1 Protein, G protein-coupled receptor kinase 2 Protein, Tsp_00497 Protein, grk2 Protein, Grk2 Protein, GRK2 Protein
- Background
- Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of th. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
- Molecular Weight
- 29.7 kDa
- UniProt
- P25098
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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