LINGO1 Protein (AA 37-555) (His tag)
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- Target See all LINGO1 Proteins
- LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 37-555
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LINGO1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- PPRCECSAQD RAVLCHRKRF VAVPEGIPTE TRLLDLGKNR IKTLNQDEFA SFPHLEELEL NENIVSAVEP GAFNNLFNLR TLGLRSNRLK LIPLGVFTGL SNLTKLDISE NKIVILLDYM FQDLYNLKSL EVGDNDLVYI SHRAFSGLNS LEQLTLEKCN LTSIPTEALS HLHGLIVLRL RHLNINAIRD YSFKRLYRLK VLEISHWPYL DTMTPNCLYG LNLTSLSITH CNLTAVPYLA VRHLVYLRFL NLSYNPIGTI EGSMLHELLR LQEIQLVGGQ LAVVEPYAFR GLNYLRVLNV SGNQLTTLEE SAFHSVGNLE TLILDSNPLA CDCRLLWVFR RRWRLNFNRQ QPTCATPEFV QGKEFKDFPD VLLPNYFTCR RAHIRDRKAQ QVFVDEGHTV QFVCRADGDP PPAILWLSPR KHLVSAKSNG RLTVFPDGTL EVRYAQVQDN GTYLCIAANA GGNDSMPAHL HVRSYSPDWP HQPNKTFAFI SNQPGEGEAN STRATVPFPF DIKTLIIAT
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product LINGO1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))
- Alternative Name
- LIGO1 (LINGO1 Products)
- Synonyms
- lern1 Protein, lrrn6a Protein, unq201 Protein, DKFZp459P0736 Protein, LERN1 Protein, LRRN6A Protein, UNQ201 Protein, 4930471K13Rik Protein, AV148400 Protein, LINGO-1 Protein, Lrrn6a Protein, leucine rich repeat and Ig domain containing 1 Protein, LINGO1 Protein, lingo1 Protein, Lingo1 Protein
- Background
- Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.1 Publication
- Molecular Weight
- 62.9 kDa
- UniProt
- Q9D1T0
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