ATG16L1 Protein (AA 1-607, full length) (His-SUMO Tag)
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- Target See all ATG16L1 Proteins
- ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-607
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ATG16L1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSSGLRAADF PRWKRHISEQ LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK HDVPNRHEIS PGHDGTWNDN QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQRK DREMQMNEAK IAECLQTISD LETECLDLRT KLCDLERANQ TLKDEYDALQ ITFTALEGKL RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI EVIVDETSDH TEETSPVRAI SRAATKRLSQ PAGGLLDSIT NIFGRRSVSS FPVPQDNVDT HPGSGKEVRV PATALCVFDA HDGEVNAVQF SPGSRLLATG GMDRRVKLWE VFGEKCEFKG SLSGSNAGIT SIEFDSAGSY LLAASNDFAS RIWTVDDYRL RHTLTGHSGK VLSAKFLLDN ARIVSGSHDR TLKLWDLRSK VCIKTVFAGS SCNDIVCTEQ CVMSGHFDKK IRFWDIRSES IVREMELLGK ITALDLNPER TELLSCSRDD LLKVIDLRTN AIKQTFSAPG FKCGSDWTRV VFSPDGSYVA AGSAEGSLYI WSVLTGKVEK VLSKQHSSSI NAVAWSPSGS HVVSVDKGCK AVLWAQY
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product ATG16L1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))
- Alternative Name
- A16L1 (ATG16L1 Products)
- Synonyms
- APG16L Protein, ATG16A Protein, ATG16L Protein, IBD10 Protein, WDR30 Protein, 1500009K01Rik Protein, Apg16l Protein, Atg16l Protein, Wdr30 Protein, atg16 Protein, atg16l Protein, fb57e05 Protein, wu:fb57e05 Protein, zgc:110147 Protein, autophagy related 16 like 1 Protein, autophagy related 16-like 1 (S. cerevisiae) Protein, autophagy related 16-like 1 Protein, autophagy related 16 like 1 S homeolog Protein, ATG16 autophagy related 16-like 1 (S. cerevisiae) Protein, ATG16L1 Protein, Atg16l1 Protein, atg16l1 Protein, atg16l1.S Protein
- Background
- Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a mbrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal mbrane.
- Molecular Weight
- 84.22 kDa
- UniProt
- Q676U5
- Pathways
- Autophagy
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