TLR7 Protein (AA 27-348, partial) (GST tag)
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- Target See all TLR7 Proteins
- TLR7 (Toll-Like Receptor 7 (TLR7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-348, partial
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TLR7 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- FRWFPKTLPC EVKVNIPEAH VIVDCTDKHL TEIPEGIPTN TTNLTLTINH IPSISPDSFR RLNHLEEIDL RCNCVPVLLG SKANVCTKRL QIRPGSFSGL SDLKALYLDG NQLLEIPQDL PSSLHLLSLE ANNIFSITKE NLTELVNIET LYLGQNCYYR NPCNVSYSIE KDAFLVMRNL KVLSLKDNNV TAVPTTLPPN LLELYLYNNI IKKIQENDFN NLNELQVLDL SGNCPRCYNV PYPCTPCENN SPLQIHDNAF NSLTELKVLR LHSNSLQHVP PTWFKNMRNL QELDLSQNYL AREIEEAKFL HFLPNLVELD FS
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product TLR7 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TLR7 (Toll-Like Receptor 7 (TLR7))
- Alternative Name
- TLR7 (TLR7 Products)
- Synonyms
- TLR7-like Protein, RGD1563357 Protein, toll like receptor 7 Protein, toll-like receptor 7 Protein, TLR7 Protein, Tlr7 Protein
- Background
- Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
- Molecular Weight
- 64.2 kDa
- UniProt
- P58681
- Pathways
- TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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