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CD43 Protein (AA 20-253) (His-SUMO Tag)

SPN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710412
  • Target See all CD43 (SPN) Proteins
    CD43 (SPN) (Sialophorin (SPN))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-253
    Origin
    • 7
    • 3
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CD43 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    STTAVQTPTS GEPLVSTSEP LSSKMYTTSI TSDPKADSTG DQTSALPPST SINEGSPLWT SIGASTGSPL PEPTTYQEVS IKMSSVPQET PHATSHPAVP ITANSLGSHT VTGGTITTNS PETSSRTSGA PVTTAASSLE TSRGTSGPPL TMATVSLETS KGTSGPPVTM ATDSLETSTG TTGPPVTMTT GSLEPSSGAS GPQVSSVKLS TMMSPTTSTN ASTVPFRNPD ENSR
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product SPN Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    CD43 (SPN) (Sialophorin (SPN))
    Alternative Name
    LEUK (SPN Products)
    Synonyms
    CD43 Protein, GALGP Protein, GPL115 Protein, LSN Protein, A630014B01Rik Protein, Cd43 Protein, Galgp Protein, Ly-48 Protein, Ly48 Protein, Lsn Protein, Lsn1 Protein, gpL115 Protein, sialophorin Protein, SPN Protein, Spn Protein
    Background
    One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 . During T-cell activation is actively roved from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response .
    Molecular Weight
    39.44 kDa
    UniProt
    P16150
    Pathways
    Regulation of Leukocyte Mediated Immunity
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