CD43 Protein (AA 20-253) (His-SUMO Tag)
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- Target See all CD43 (SPN) Proteins
- CD43 (SPN) (Sialophorin (SPN))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-253
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CD43 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- STTAVQTPTS GEPLVSTSEP LSSKMYTTSI TSDPKADSTG DQTSALPPST SINEGSPLWT SIGASTGSPL PEPTTYQEVS IKMSSVPQET PHATSHPAVP ITANSLGSHT VTGGTITTNS PETSSRTSGA PVTTAASSLE TSRGTSGPPL TMATVSLETS KGTSGPPVTM ATDSLETSTG TTGPPVTMTT GSLEPSSGAS GPQVSSVKLS TMMSPTTSTN ASTVPFRNPD ENSR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product SPN Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Alternative Name
- LEUK (SPN Products)
- Synonyms
- CD43 Protein, GALGP Protein, GPL115 Protein, LSN Protein, A630014B01Rik Protein, Cd43 Protein, Galgp Protein, Ly-48 Protein, Ly48 Protein, Lsn Protein, Lsn1 Protein, gpL115 Protein, sialophorin Protein, SPN Protein, Spn Protein
- Background
- One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 . During T-cell activation is actively roved from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response .
- Molecular Weight
- 39.44 kDa
- UniProt
- P16150
- Pathways
- Regulation of Leukocyte Mediated Immunity
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