RGS2 Protein (AA 1-211, full length) (His-SUMO Tag)
-
- Target See all RGS2 Proteins
- RGS2 (Regulator of G-Protein Signaling 2 (RGS2))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-211
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RGS2 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MQSAMFLAVQ HDCRPMDKSA GSGHKSEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQAFI KPSPEEAQLW SEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product RGS2 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- RGS2 (Regulator of G-Protein Signaling 2 (RGS2))
- Alternative Name
- RGS2 (RGS2 Products)
- Synonyms
- G0S8 Protein, GOS8 Protein, fa96c08 Protein, wu:fa96c08 Protein, wu:fj08f11 Protein, zgc:91965 Protein, g0s8 Protein, regulator of G protein signaling 2 Protein, regulator of G-protein signaling 2 Protein, regulator of G-protein signaling 2, 24kDa Protein, regulator of G-protein signaling 2 L homeolog Protein, RGS2 Protein, Rgs2 Protein, rgs2 Protein, rgs2.L Protein
- Background
- Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving th into their inactive GDP-bound form. May play a role in leukogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
- Molecular Weight
- 40.4 kDa
- UniProt
- P41220
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
-