Neuroglobin Protein (NGB) (AA 1-151, full length) (His-SUMO Tag)
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- Target See all Neuroglobin (NGB) Proteins
- Neuroglobin (NGB)
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-151
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Neuroglobin protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product NGB Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Neuroglobin (NGB)
- Alternative Name
- NGB (NGB Products)
- Synonyms
- NGB Protein, ngb Protein, neuroglobin Protein, neuroglobin L homeolog Protein, NGB Protein, Ngb Protein, ngb Protein, ngb.L Protein
- Background
- Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell mbranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
- Molecular Weight
- 32.9 kDa
- UniProt
- Q9NPG2
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