Kallikrein 7 Protein (KLK7) (AA 28-253) (His tag)
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- Target See all Kallikrein 7 (KLK7) Proteins
- Kallikrein 7 (KLK7)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-253
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Kallikrein 7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- HHSSGLVPRG SHMDDDDKII DGAPCARGSH PWQVALLSGN QLHCGGVLVN ERWVLTAAHC KMNEYTVHLG SDTLGDRRAQ RIKASKSFRH PGYSTQTHVN DLMLVKLNSQ ARLSSMVKKV RLPSRCEPPG TTCTVSGWGT TTSPDVTFPS DLMCVDVKLI SPQDCTKVYK DLLENSMLCA GIPDSKKNAC NGDSGGPLVC RGTLQGLVSW GTFPCGQPND PGVYTQVCKF TKWINDTMKK HR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product KLK7 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Kallikrein 7 (KLK7)
- Alternative Name
- KLK7 (KLK7 Products)
- Synonyms
- Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein
- Background
- May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
- Molecular Weight
- 55.8 kDa
- UniProt
- P49862
- Pathways
- Complement System
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