ID1 Protein (AA 1-155, full length) (His-SUMO Tag)
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- Target See all ID1 Proteins
- ID1 (Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-155
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ID1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MKVASGSTAT AAAGPSCALK AGKTASGAGE VVRCLSEQSV AISRCAGGAG ARLPALLDEQ QVNVLLYDMN GCYSRLKELV PTLPQNRKVS KVEILQHVID YIRDLQLELN SESEVGTPGG RGLPVRAPLS TLNGEISALT AEAACVPADD RILCR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product ID1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- ID1 (Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))
- Alternative Name
- ID1 (ID1 Products)
- Synonyms
- ID1 Protein, id6 Protein, cb108 Protein, wu:fb57e11 Protein, AI323524 Protein, D2Wsu140e Protein, Idb1 Protein, bHLHb24 Protein, ID125A Protein, ID Protein, inhibitor of DNA binding 1 Protein, inhibitor of DNA binding 1, HLH protein Protein, id1 Protein, ID1 Protein, Id1 Protein
- Background
- Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer .
- Molecular Weight
- 32.1 kDa
- UniProt
- P41134
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