HIST1H2BD Protein (AA 2-126) (His-SUMO Tag)
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- Target See all HIST1H2BD Proteins
- HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-126
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HIST1H2BD protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- PEPSKSAPAP KKGSKKAITK AQKKDGKKRK RSRKESYSIY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSSK
- Purification
- SDS-PAGE
- Purity
- > 90 %
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))
- Alternative Name
- H2B1B (HIST1H2BD Products)
- Synonyms
- HIST1H2BI Protein, H2B.1B Protein, H2B/b Protein, H2BFB Protein, HIRIP2 Protein, dJ221C16.6 Protein, histone cluster 1, H2bd Protein, histone cluster 1 H2B family member d Protein, HIST1H2BD Protein
- Background
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.
- Molecular Weight
- 29.81 kDa
- UniProt
- P33778
- Pathways
- Telomere Maintenance
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