Frataxin Protein (FXN) (AA 78-207) (His-SUMO Tag)
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- Target See all Frataxin (FXN) Proteins
- Frataxin (FXN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 78-207
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Frataxin protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- LGTLDNPSSL DETAYERLAE ETLDSLAEFF EDLADKPYTL EDYDVSFGDG VLTIKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAREL TKALNTKLDL SSLAYSGKGT
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product FXN Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Frataxin (FXN)
- Alternative Name
- FRDA (FXN Products)
- Synonyms
- zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
- Background
- Promotes the biosynthesis of he and assbly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 .
- Molecular Weight
- 30.4 kDa
- UniProt
- O35943
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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