Ephrin B3 Protein (EFNB3) (AA 28-227) (His tag)
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- Target See all Ephrin B3 (EFNB3) Proteins
- Ephrin B3 (EFNB3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-227
- Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Ephrin B3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- LSLEPVYWNS ANKRFQAEGG YVLYPQIGDR LDLLCPRARP PGPHSSPSYE FYKLYLVEGA QGRRCEAPPA PNLLLTCDRP DLDLRFTIKF QEYSPNLWGH EFRSHHDYYI IATSDGTREG LESLQGGVCL TRGMKVLLRV GQSPRGGAVP RKPVSEMPME RDRGAAHSAE PGRDTIPGDP SSNATSRGAE GPLPPPSMPA
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product EFNB3 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Ephrin B3 (EFNB3)
- Alternative Name
- EFNB3 (EFNB3 Products)
- Synonyms
- efnb3-A Protein, EphB3 Protein, EFNB3 Protein, efnb3 Protein, id:ibd5049 Protein, zgc:111938 Protein, EFL-6 Protein, ELF-3 Protein, Elk-L3 Protein, Epl8 Protein, LERK-8 Protein, NLERK-2 Protein, ELK-L3 Protein, RGD1565678 Protein, EFL6 Protein, EPLG8 Protein, LERK8 Protein, ephrin B3 Protein, ephrin-B3 L homeolog Protein, ephrin-B3b Protein, ephrin-B3 Protein, EFNB3 Protein, efnb3.L Protein, efnb3b Protein, efnb3 Protein, Efnb3 Protein
- Background
- Cell surface transmbrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.
- Molecular Weight
- 26.1 kDa
- UniProt
- O35393
- Pathways
- RTK Signaling
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