CSNK1A1 Protein (AA 2-337) (His tag)

Catalog No. ABIN5709341

Product Details

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Protein Type: Recombinant

Protein Characteristics: AA 2-337

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CSNK1A1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: ASSSGSKAEF IVGGKYKLVR KIGSGSFGDI YLAINITNGE EVAVKLESQK ARHPQLLYES KLYKILQGGV GIPHIRWYGQ EKDYNVLVMD LLGPSLEDLF NFCSRRFTMK TVLMLADQMI SRIEYVHTKN FIHRDIKPDN FLMGIGRHCN KLFLIDFGLA KKYRDNRTRQ HIPYREDKNL TGTARYASIN AHLGIEQSRR DDMESLGYVL MYFNRTSLPW QGLKAATKKQ KYEKISEKKM STPVEVLCKG FPAEFAMYLN YCRGLRFEEA PDYMYLRQLF RILFRTLNHQ YDYTFDWTML KQKAAQQAAS SSGQGQQAQT PTGKQTDKTK SNMKGF

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: KC1A (CSNK1A1 Products)

Synonyms: CK1 Protein, CK1a Protein, CKIa Protein, HLCDGP1 Protein, PRO2975 Protein, 2610208K14Rik Protein, 4632404G05Rik Protein, 5430427P18Rik Protein, Csnk1a Protein, CHUNP6894 Protein, ck1alpha Protein, wu:fb65a02 Protein, wu:fi30h04 Protein, wu:fj19c11 Protein, zgc:92158 Protein, KER1 Protein, ck1 Protein, CKIALPHA Protein, CK-II Protein, CSNK2A1 Protein, CG2028 Protein, CK I Protein, CK1alpha Protein, CKI Protein, CKI alpha Protein, CKIalpha Protein, CkIa Protein, Dmel\\CG2028 Protein, PKA-C Protein, anon-WO03040301.93 Protein, anon-WO03040301.95 Protein, ck1a Protein, dmCK1 Protein, dmckI Protein, l(1)G0492 Protein, casein kinase 1 alpha 1 Protein, casein kinase 1, alpha 1 Protein, keratin 1 Protein, casein kinase 1 alpha 1 L homeolog Protein, casein kinase 2 alpha 1 Protein, Casein kinase Ialpha Protein, CSNK1A1 Protein, Csnk1a1 Protein, csnk1a1 Protein, KRT1 Protein, csnk1a1.L Protein, CSNK2A1 Protein, CkIalpha Protein

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.

Molecular Weight: 42.9 kDa

UniProt: P48729

Pathways: WNT Signaling, Hedgehog Signaling