CCL21 Protein (AA 24-134) (GST tag)
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- Target See all CCL21 Proteins
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-134
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CCL21 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CCL21 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Alternative Name
- CCL21 (CCL21 Products)
- Synonyms
- 6Ckine Protein, CKb9 Protein, ECL Protein, SCYA21 Protein, SLC Protein, TCA4 Protein, ccl21 Protein, Ccl21b Protein, C-C motif chemokine ligand 21 Protein, C-C motif chemokine 21 Protein, CCL21 Protein, ccl21 Protein, Ccl21 Protein
- Background
- Inhibits hopoiesis and stimulates chotaxis. Chotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
- Molecular Weight
- 39.6 kDa
- UniProt
- O00585
- Pathways
- Regulation of Actin Filament Polymerization
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