BIM Protein (AA 1-198, full length) (His-SUMO Tag)
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- Target See all BIM (BCL2L11) Proteins
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-198, full length
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BIM protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MAKQPSDVSS ECDREGRQLQ PAERPPQLRP GAPTSLQTEP QGNPEGNHGG EGDSCPHGSP QGPLAPPASP GPFATRSPLF IFMRRSSLLS RSSSGYFSFD TDRSPAPMSC DKSTQTPSPP CQAFNHYLSA MASMRQAEPA DMRPEIWIAQ ELRRIGDEFN AYYARRVFLN NYQAAEDHPR MVILRLLRYI VRLVWRMH
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product BCL2L11 Protein
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BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-112) protein (GST tag)
BCL2L11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-100) protein (GST tag)BCL2L11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-109) protein (GST tag)BCL2L11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198), (full length) protein (His tag)BCL2L11 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Alternative Name
- B2L11 (BCL2L11 Products)
- Synonyms
- bim Protein, BAM Protein, BIM Protein, BOD Protein, 1500006F24Rik Protein, Bim Protein, Bod Protein, BimL Protein, BIMEL Protein, BCL2-like 11 Protein, BCL2 like 11 Protein, BCL2-like 11 (apoptosis facilitator) Protein, bcl2l11 Protein, BCL2L11 Protein, Bcl2l11 Protein
- Background
- Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
- Molecular Weight
- 38.17 kDa
- UniProt
- O43521
- Pathways
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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