Hemopexin Protein (HPX)
Quick Overview for Hemopexin Protein (HPX) (ABIN5662823)
Target
See all Hemopexin (HPX) ProteinsProtein Type
Origin
Source
Purity
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Cross-Reactivity (Details)
 - Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
 
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Application Notes
 - For use in: SDS
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Comment
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Extinction Coefficient: 1.97
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Restrictions
 - For Research Use only
 
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Format
 - Lyophilized
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Buffer
 - 11.9 mM phosphate, 137 mM NaCl, 2.7 mM KCl, pH 7.4.
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Storage
 - -20 °C
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Storage Comment
 - -20°C
 
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                                            : "Nano reversed phase versus nano hydrophilic interaction liquid chromatography on a chip in the analysis of hemopexin glycopeptides."    in: Journal of chromatography. A, Vol. 1519, pp. 152-155, (2017)         (PubMed).        
: "Study of structure-dependent chromatographic behavior of glycopeptides using reversed phase nanoLC." in: Electrophoresis, Vol. 38, Issue 17, pp. 2193-2199, (2017) (PubMed).
: "IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections." in: Science immunology, Vol. 2, Issue 8, (2017) (PubMed).
: "Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury." in: Antioxidants & redox signaling, Vol. 24, Issue 2, pp. 99-112, (2016) (PubMed).
: "Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 36, Issue 6, pp. 1152-63, (2016) (PubMed).
: "Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase-1." in: FEBS open bio, Vol. 6, Issue 9, pp. 876-84, (2016) (PubMed).
: "Purified and recombinant hemopexin: protease activity and effect on neutrophil chemotaxis." in: Molecular medicine (Cambridge, Mass.), (2016) (PubMed).
: "Sickle Cell Hemoglobin in the Ferryl State Promotes βCys-93 Oxidation and Mitochondrial Dysfunction in Epithelial Lung Cells (E10)." in: The Journal of biological chemistry, Vol. 290, Issue 46, pp. 27939-58, (2015) (PubMed).
 
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                                            : "Nano reversed phase versus nano hydrophilic interaction liquid chromatography on a chip in the analysis of hemopexin glycopeptides."    in: Journal of chromatography. A, Vol. 1519, pp. 152-155, (2017)         (PubMed).        
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- Hemopexin (HPX)
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Alternative Name
 - Hemopexin
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Background
 - HPX, HX, Hpxn, beta-1B-glycoprotein, transporter
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Molecular Weight
 - 57 kDa
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Pathways
 - Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
 
Target
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