AIMP1 Protein (partial) (His tag)
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- Target See all AIMP1 Proteins
- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
- Protein Type
- Recombinant
- Protein Characteristics
- partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AIMP1 protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Sequence
- Ala 2 - Lys 312
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Top Product
- Discover our top product AIMP1 Protein
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- Application Notes
- This recombinant protein can be used for WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
- Alternative Name
- AIMP1 (AIMP1 Products)
- Synonyms
- EMAP2 Protein, EMAPII Protein, HLD3 Protein, SCYE1 Protein, p43 Protein, wu:fa95a05 Protein, zgc:154081 Protein, AIMP1 Protein, 9830137A06Rik Protein, AIMP1/p43 Protein, Emap2 Protein, Scye1 Protein, scye1 Protein, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Protein, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 Protein, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog Protein, AIMP1 Protein, aimp1 Protein, Aimp1 Protein, aimp1.S Protein
- Background
- Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.
- Molecular Weight
- 35.2 kDa
- Gene ID
- 9255
- NCBI Accession
- NP_004748
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