ACVA Protein (partial)
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- Target See all ACVA Proteins
- ACVA (Activin A (ACVA))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- partial
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Origin
- Human
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Source
- HEK-293 Cells
- Application
- Western Blotting (WB), ELISA
- Sequence
- Gly 311 - Ser 426
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Biological Activity Comment
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Measured by its binding ability in a functional ELISA. Immobilized Human Activin A, Tag Free at 10 μg/mL (100 uL/well) can bind Human ACVR1B, Fc Tag with a linear range of 0.3-2.5 μg/mL (QC tested).
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- Discover our top product ACVA Protein
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Activin A (ACVA) (AA 311-426) (Active) protein
ACVA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Activin A (ACVA) (AA 311-426) proteinACVA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Activin A (ACVA) (AA 309-424) protein (His tag)ACVA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Activin A (ACVA) (AA 309-424) protein (His tag)ACVA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Application Notes
- This recombinant protein can be used for E, WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 0.056 % TFA in 60 % ACN
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- ACVA (Activin A (ACVA))
- Alternative Name
- Activin A (ACVA Products)
- Synonyms
- inhibin beta A subunit Protein, Inhba Protein
- Background
- Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely inhibin down regulates FSH synthesis and inhibits FSH secretion.Activins are nonglycosylated homodimers or heterodimers of various beta subunits (betaA, betaB, betaC, and betaE in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two betaA chains. The betaA subunit can also heterodimerize with a betaB or betaC subunit to form Activin AB and Activin AC, respectively. The 14 kDa mature human betaA chain shares 100 % amino acid sequence identity with bovine, feline, mouse, porcine, and rat betaA.
- Molecular Weight
- 13 kDa
- Gene ID
- 3624
- UniProt
- P08476
- Pathways
- Hormone Transport, Peptide Hormone Metabolism
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