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IgG Fc (partial) protein (His tag)

Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Catalog No. ABIN5608319
  • Target
    IgG Fc
    Protein Type
    Recombinant
    Protein Characteristics
    partial
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    His tag
    Application
    Western Blotting (WB)
    Sequence
    Glu 99 - Lys 330
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Endotoxin level is less than 1.0 EU per ug by the LAL method.
  • Application Notes
    This recombinant protein can be used for WB.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • Target
    IgG Fc
    Target Type
    Antibody
    Background
    Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
    Molecular Weight
    27 kDa
    Gene ID
    3500
    UniProt
    P01857
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