DLL1 Protein (partial) (His tag)
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- Target See all DLL1 Proteins
- DLL1 (delta-Like 1 (DLL1))
- Protein Type
- Recombinant
- Protein Characteristics
- partial
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DLL1 protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Sequence
- Gln 18 - Gly 540
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
- Top Product
- Discover our top product DLL1 Protein
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- Application Notes
- This recombinant protein can be used for WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Target
- DLL1 (delta-Like 1 (DLL1))
- Alternative Name
- DLL1 (DLL1 Products)
- Synonyms
- X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein
- Background
- Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
- Molecular Weight
- 58.4 kDa
- Gene ID
- 28514
- NCBI Accession
- NP_005609
- UniProt
- O00548
- Pathways
- Notch Signaling, Stem Cell Maintenance
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