AZGP1 Protein (AA 21-298)
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- Target See all AZGP1 Proteins
- AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-298
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human full-length zinc-alpha-2-glycoprotein (aa 21-298) is untagged.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product AZGP1 Protein
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alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1) (AA 1-298) protein (GST tag)
AZGP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1) (AA 22-298) protein (GST tag)AZGP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1) (AA 21-298) protein (His tag)AZGP1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))
- Alternative Name
- Zinc-alpha-2-glycoprotein (AZGP1 Products)
- Synonyms
- Zag Protein, ZA2G Protein, ZAG Protein, ZA2GA Protein, Zna2gp Protein, alpha-2-glycoprotein 1, zinc Protein, alpha-2-glycoprotein 1, zinc-binding Protein, Azgp1 Protein, AZGP1 Protein
- Background
- Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
- Molecular Weight
- ~30kDa
- UniProt
- P25311
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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