Annexin V Protein (FITC,GST tag)
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- Target See all Annexin V (ANXA5) Proteins
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Annexin V protein is labelled with FITC,GST tag.
- Application
- SDS-PAGE (SDS), Flow Cytometry (FACS)
- Specificity
- Binds to phosphatidylserine (PS).
- Cross-Reactivity
- Human
- Characteristics
- Recombinant human annexin V fused to a GST-tag.
- Purity
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product ANXA5 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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This protein can be used for the detection of apoptotic cells by flow cytometry or immunofluorescence (100 tests/0.5ml).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS, pH 7.4, containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: +4°C
Stable for at least 1 year after receipt when stored at +4°C. - Expiry Date
- 12 months
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- Target
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
- Alternative Name
- Annexin V (ANXA5 Products)
- Synonyms
- anx Protein, anx5 Protein, ANX V Protein, anxa5 Protein, cb989 Protein, wu:fa98f06 Protein, wu:fj10f10 Protein, MGC89158 Protein, ANX5 Protein, ENX2 Protein, PP4 Protein, RPRGL3 Protein, Anx5 Protein, R74653 Protein, LC5 Protein, enx2 Protein, annexin A5 Protein, annexin A5b Protein, Annexin A5 Protein, annexin A5 L homeolog Protein, ANXA5 Protein, anxa5b Protein, anxa5 Protein, Anxa5 Protein, anxa5.L Protein
- Background
- Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
- Molecular Weight
- ~52kDa (SDS-PAGE)
- UniProt
- P08758
- Pathways
- Apoptosis
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